Abstract: The synthesis of 4-amino-2-quinolones 2 by thermal reaction of
4-hydroxy-2-quinolones 1 with benzylammonium chloride is described.
The mixture is heated without solvent and the primary product, the
4-benzylamino-2-quinolone 3 is debenzylated at the reaction conditions.
In some cases a mixture of 2 and 3 is formed depending on
the substituent in position 3.
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