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24.Syntheses of indoles and isochinolones from phenylmalonylheterocycles
Stadlbauer W., Kappe Th. Monatsh. Chem. 115 (1984) 467-475

Abstract: A new synthesis of the indole system has been achieved by cyclodehydrogenation of amino phenylmalonate heterocycles. Thus, the 4-amino coumarins 1a,b or the 4-amino-2-quinolones 1c-g are converted to the indoles 2 with palladium on charcoal in boiling diphenyl ether. The reaction of the aminocompounds 1 with diphenyl carbonate yields the fused polycyclic isoquinolines 4.


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