Abstract: Nitration of 3-substituted-4-hydroxy-2(1H)-quinolones with nitric acid leads
either to 3-nitro- or 3-hydroxyquinolinediones, depending on the reaction conditions.
3-Substituted-3-hydroxyquinolinediones are also obtained by oxidative
hydroxylation with peroxyacetic acid. Amination of 3-substituted-3-chloroquinolinediones) with
ammonium hydroxide predominantly leads again to 3-substituted-3-hydroxyquinoline-
diones, only in one case the 3-aminoquinolinedione could be isolated. With
morpholine ore pyridine as amines the expected 3-aminoquinolinediones were obtained.
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