Abstract: Depending on the ester substituent, diethyl 2-(3-nitro-2-oxo-4-
quinolinyl)-malonates give upon thermolysis ethyl 2-(3-nitro-2-
oxo-4-quinolinyl)-acetates, whereas dimethyl 2-(3-nitro-2-oxo-
4-quinolinyl)-malonates cyclize to give 1-methoxycarbonyl-
isoxazolo[3,4-c]quinolin-4(5H)-ones. The necessary reaction
conditions can be obtained easily with the help of DSC.
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