Stadlbauer W., Prattes S. , Täubl A. E. ,
Proceedings of the First International Electronic Conference on Synthetic Organic
S.-K. Lin, E. Pombo-Villar (Eds), MPDI, Basel, 1999;
CD-ROM, ISBN 3-906980-00-6, A0020.
Abstract: Differential Scanning Calorimetry (DSC) provides useful
information in organic synthesis in the stage of planning thermolytical
reactions. This information can be obtained before the reaction itself is
performed and include the temperature range of the planned reaction, hints on
subsequent rearrangement and decomposition reactions, choice of suitable
solvents and safety precautions in exothermic processes.
Another point of interest is that also reactions with two reaction partners and
the influence of solvents on the reaction temperature can be studied.
In this paper three examples of DSC applications in organic synthesis
are presented, which deal mainly with thermolytic reactions of ortho-substituted
organic azides and subsequent reactions.
Reprint as pdf-file on request